A picture is worth a thousand base pairs

A small but powerful toolset makes sharing genomic data visualizations straightforward.

Unraveling Evolutionary Patterns

We are using genomics to uncover clues about species extinction, to learn how to save vulnerable populations and to see what this teaches us about our future on earth.

Identifying the Underpinnings of Disease

Diseases like cancer have a unique genetic signature that can be digitized, deconstructed and compared with healthy biology. It’s a clinical problem with a computer science solution.

Uniting Global Communities

We have led the effort to define genomics data-sharing standards by co-founding the GA4GH, with more than 450 organizational members from more than 40 countries

Platforms for Life-Saving Treatments

We can match individual tumor RNA with tumors in the largest public cancer genome database in the world — uncovering potential treatment options for patients with “incurable” cancer.

UCSC’s Genomics Institute settles into new Delaware Avenue headquarters

The move to 2300 Delaware Ave. coincides with the formal establishment of the Genomics Institute as an Organized Research Unit at UC Santa Cruz

Welcome to the UC Santa Cruz Genomics Institute

BRCA Exchange: Data Sharing for the Benefit of Science and Medicine

DNA Testing 2.0: The Near Future of Population Genomics

$8.5 million gift supports UC Santa Cruz Genomics Institute

Tim Stephens | UCSC | October 08, 2019       UC Santa Cruz has received an anonymous gift of $8.5 million to support the Genomics Institute’s pioneering interdisciplinary research. The gift, which will be made in annual installments over the next ten...

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A picture is worth a thousand base pairs

A picture is worth a thousand base pairs

When Adam Siepel was building algorithms for evolutionary genomics as part of his PhD, he wasn’t thinking about visualization. But, as a graduate student in the laboratory of computational biologist David Haussler, at the University of California, Santa Cruz (UCSC), he happened to sit next to the software engineers who were building and maintaining a tool called the UCSC Genome Browser. These engineers helped Siepel to make his algorithms publicly available as a track, or data overlay, that anyone could explore.

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Whole genome sequencing could help save pumas from inbreeding

Whole genome sequencing could help save pumas from inbreeding

When students at UC Santa Cruz found a dead mule deer on campus, they figured it had been killed by coyotes. Wildlife biologist Chris Wilmers rigged up a video camera to spy on the carcass at night. But the animal that crept out of the shadows to dine on the deer was no coyote—it was a mountain lion.

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Nanopore native RNA sequencing of a human poly(A) transcriptome

Rachael E. Workman, Alison D. Tang, Paul S. Tang, Miten Jain, John R. Tyson, Roham Razaghi, Philip C. Zuzarte, Timothy Gilpatrick, Alexander Payne, Joshua Quick, Norah Sadowski, Nadine Holmes, Jaqueline Goes de Jesus, Karen L. Jones, Cameron M. Soulette, Terrance P....

BaMBA – Biology and Mathematics in the Bay Area

BaMBA is a one-day meeting aimed at exploring the role of mathematics in biology in an informal atmosphere. Going beyond traditional applied mathematics, the topics include applications of algebraic, topological, statistical and computational methods. Our goal is to encourage dialogue between researchers and students from different disciplines in an atmosphere that promotes the open exchange of ideas and viewpoints.  In addition to the four invited lectures, this year we will have a diversity panel and a poster session. 

Saturday, December 7, 2019 
Engineering RM 152
9:00 am – 7:00 pm

“The Genomics Institute has been coming up with approaches to treating pediatric cancer that have never been tried before.”

– John “Bud” and Rebecca Colligan, who established the Colligan Presidential Chair