Nature

“We are responsible for the world in which we find ourselves, if only because we are the only sentient force which can change it.”James Baldwin

The UC Santa Cruz Genomics Institute unlocks the world’s genomic information to drive the next great leap in understanding biodiversity, conservation and evolutionary biology.

These are some of our focus areas. Select one to learn more.

Evolutionary
& Conservation Genomics

Evolutionary and conservation genomics can help us understand what went wrong with extinct species such as the passenger pigeon, help endangered species, restore ancient diversity to current species, become better stewards of our planet, and find new ways to improve human health.
Research in Ed Green’s lab explores archaic ancestry in the human genome from our relatives the Neanderthals and Denosivans.

 

Genome 10K Project

Banana Slug Genome

UC Santa Cruz is world-renowned for its genomics research; namely, sequencing and publishing the human genome. We have spent an immense amount of time focusing on what makes us unique, now we are unraveling the mysteries of our slimy mascot. We are sequencing the genome of the banana slug.

#sluggenome

UC Santa Cruz Genomics Institute’s sequencing experts Nader Pourmand and Mark Akeson will use sophisticated technology to extract DNA from a sample, creating long chains of nucleic acids (A, C, T, and G). Assisting them in this endeavor will be UC Santa Cruz undergraduate students, lending a hand in sample preparation, sequencing, and developing DNA libraries during winter quarter. This will be an incredible opportunity for students to be involved in hands-on research

During spring quarter 2015, UC Santa Cruz faculty members Ed Green and Kevin Karplus led a team of graduate students in assembling the genome sequence and annotating the data collected from the sample. This will make the information more accessible and allow researchers to analyze the extensive quantity of information. The students made considerable progress, and many are continuing through the summer.

There are stark differences between our banana slug, Ariolimax dolichophallus, and its close relatives. The results of this project will provide invaluable insight on species diversity, with implications for understanding the evolutionary differentiation in reproductive and sexual behavior. There is not an abundance of information on our unique mascot, but this investigation will provide profound knowledge on our slimy species. In addition, this information will contribute to conservation efforts of animals world-wide.
To make this feat a reality, the campus undertook a crowdfunding campaign in October and November 2014 that raised $21,443 from 139 donors.