“We are responsible for the world in which we find ourselves, if only because we are the only sentient force which can change it.”
– James Baldwin
The UC Santa Cruz Genomics Institute unlocks the world’s genomic information to drive the next great leap in understanding biodiversity, conservation, and evolutionary biology.
The following links below list some of our focus areas. Click on each one to learn more about them.
Evolutionary & Conservation Genomics
The Genome 10K
Genomics Institute researchers led by faculty members Beth Shapiro, Ed Green
Genome 10K Project
The Genome 10K Project was co-founded by David Haussler, along with Steve O’Brien. In addition, they have collaborated most recently with the Theodosius Dobzhansky Center for Genome Bioinformatics of St. Petersburg State University (Russia) and Oliver Ryder from the Zoological Society of San Diego to assemble a genomic zoo. The project will create a collection of DNA sequences capturing the genomic diversity of 10,000 vertebrate species. In addition, the zoo will become a resource for worldwide conservation efforts and the life sciences.
The route of cost reduction in DNA sequencing suggests that within a few years, it will be possible to sequence a fully representative set of more than 10,000 genomes. This captures much of the genomic diversity
In April 2009, the project launched in a two-day workshop in Santa Cruz, California. They brought together scientists involved with tissue specimen collection to discuss the coordination of efforts. This collaboration eventually helped lay the groundwork for a large-scale sequencing and analysis project.
The Genome 10K Project‘s growing community of leading scientists representing major zoos, museums, research centers, and universities around the world is well on its way to coordinating tissue specimens and genome sequences to build a collection of 10,000 vertebrate genomes.
Evolutionary and conservation genomics can help us understand what went wrong with extinct species. Investigating extinct creatures, like the passenger pigeon, can help endangered animals by restoring ancient diversity in currently present groups.
This type of investigation will allow us to become better at supervising our planet. It will also open doors to new ways of improving human health.
Research in Ed Green’s lab explores archaic ancestry in the human genome from our relatives, the Neanderthals
Banana Slug Genome
UC Santa Cruz is known worldwide for its strong dedication towards genomics research. Specifically speaking, our efforts in sequencing and publishing the human genome.
Currently, we are unraveling the mysteries of our slimy mascot– we are sequencing the genome of the banana slug.
UC Santa Cruz Genomics Institute’s sequencing experts Nader Pourmand and Mark Akeson will use advanced technology to extract DNA from a sample, creating long chains of nucleic acids (A, C, T, and G).
UC Santa Cruz undergraduate students will assist them in this method. They take part by helping with sample preparation, sequencing, and developing DNA libraries during the winter quarter.
This will be an incredible opportunity for students to be involved in hands-on research.
During the spring quarter of 2015, UC Santa Cruz faculty members Ed Green and Kevin Karplus led a team of graduate students. Their work consisted of assembling a genome sequence and annotating the data collected from samples.
In the future, their work will make this information more accessible, giving researchers the ability to analyze the extensive amount of data.
The students made considerable progress, and many are continuing through the summer.
There are significant differences between the banana slug, Ariolimax
There is not an abundance of information on our unique mascot, but this project will provide extensive knowledge on the slimy species. In addition, this information will contribute to conservation efforts for animals worldwide.
To make this feat a reality, the campus undertook a crowdfunding campaign in October and November 2014 that raised $21,443 from 139 donors.