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TNF-α modulates genome-wide redistribution of ΔNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer.

by webmaster | May 2, 2016 | Publications

Abstract: The Cancer Genome Atlas (TCGA) network study of 12 cancer types (PanCancer 12) revealed frequent mutation of TP53, and amplification and expression of related TP63 isoform ΔNp63 in squamous cancers. Further, aberrant expression of inflammatory genes and...
UC Santa Cruz leads $11 million Center for Big Data in Translational Genomics

UC Santa Cruz leads $11 million Center for Big Data in Translational Genomics

by webmaster | Oct 9, 2014 | News

By Tim Stephens, UCSC Public Information Office The National Institutes of Health (NIH) has awarded $11 million to UC Santa Cruz to create the technical infrastructure needed for the broad application of genomics in medicine and biomedical research. This grant from...
UC Santa Cruz among top five institutions seeing growth in NIH funding

UC Santa Cruz among top five institutions seeing growth in NIH funding

by webmaster | Sep 23, 2014 | News

By Guy Lasnier, UCSC Public Information Office UC Santa Cruz is in the top five of institutions that have seen significant increases in funding from the National Institutes of Health over the past decade. At the same time a number of other institutions have suffered...

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  • Braingeneers
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  • Genome 10K
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  • UCSC Genome Browser
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